Before-and-after illustration showing ways to prevent ‘Ozempic Face’ while using GLP-1 weight loss medication.

With the increasing popularity of medications like Ozempic for weight loss and diabetes management, a side effect known
as "Ozempic face" has gained attention. This term refers to the sagging or gaunt appearance of the face that some individuals experience after significant weight loss. While this change in appearance can be unsettling, it’s important to understand that it’s a common issue during rapid weight loss, not just specific to Ozempic. Fortunately, there are ways to prevent and mitigate this effect, allowing you to enjoy the benefits of weight loss without compromising your facial health and appearance.

What Causes "Ozempic Face"?"

Ozempic face" is largely caused by fat loss in the face. As people lose weight rapidly, fat in areas like the cheeks, temples, and under the eyes can diminish, leading to a hollow or sunken appearance. The skin, especially in older adults, may not have the same elasticity it once did, which can result in sagging.

Since fat loss can occur all over the body, including the face, this side effect is common with any form of rapid weight loss—not just when using Ozempic.

Tips to Avoid or Reduce "Ozempic Face":

  1. Lose Weight Gradually- One of the most effective ways to avoid significant changes in facial appearance is to lose weight slowly and steadily. Rapid weight loss often leads to more noticeable facial volume loss. A gradual approach gives your skin more time to adjust to the changes in your body’s fat composition, reducing the risk of sagging or hollowing in the face.
  2. Hydrate, Hydrate, Hydrate- Hydration is key to maintaining skin elasticity and preventing dryness. When you lose weight, your body needs proper hydration to maintain skin health. Drinking plenty of water helps plump the skin and keeps it looking youthful and healthy.
    • Aim for 8-10 glasses of water a day to keep your skin hydrated.
    • Consider using a humidifier to add moisture to the air, especially in dry climates or during colder months.
  3. Follow a Balanced, Nutrient-Dense Diet- Eating a diet rich in vitamins, minerals, and antioxidants is essential for supporting skin health. Certain nutrients, like vitamin C, collagen, and omega-3 fatty acids, play a role in maintaining skin elasticity and firmness.
    • Include foods rich in collagen-boosting nutrients, such as berries, citrus fruits, leafy greens, and fish.
    • Add healthy fats like avocados, nuts, and seeds to your diet to support skin hydration and repair.
  4. Incorporate Strength Training-  While cardio exercises help burn calories, strength training is crucial for maintaining muscle tone and preventing sagging skin. By building muscle underneath your skin, especially in your upper body and face, you can create a firmer appearance.
    • Focus on facial exercises (also known as facial yoga) to tone the muscles in your face, such as those around the cheeks and jawline.
    • Regular strength training also improves blood circulation, delivering essential nutrients to the skin.
  5. Take Collagen Supplements- As we age, our body produces less collagen, which can contribute to skin sagging. Taking a collagen supplement can help replenish some of the collagen your body is losing and improve skin elasticity.
    • Look for supplements with collagen peptides, which are easily absorbed by the body. There’s growing evidence that collagen supplements can improve skin hydration and elasticity, making them a helpful addition to your regimen.
  6. Use Skin-Firming Products-  Incorporate anti-aging skincare products into your daily routine to help maintain the firmness and elasticity of your skin:
    • Retinoids: These vitamin A derivatives stimulate collagen production and promote skin cell turnover.
    • Hyaluronic Acid: This powerhouse ingredient helps retain moisture and plump up the skin.
    • Peptides and Antioxidants: These help repair and protect the skin’s barrier function, reducing signs of aging. Make sure to consult a dermatologist before starting a new skincare regimen, especially if you're using Ozempic or another medication for weight loss.
    • B-Complex: Promotes overall skin health by assisting in cell regeneration and repair, which is vital for keeping skin and tissues healthy and vibrant.
    • Glutathione: Often referred to as the body’s master antioxidant, Glutathione protects cells from oxidative stress, a key contributor to aging. It also enhances the body’s detoxification process, which is essential for maintaining healthy skin.
    • Vitamin C: Crucial for collagen production, Vitamin C supports the enzymes that stabilize and strengthen collagen fibers. Its antioxidant properties also shield the skin from damage caused by free radicals, promoting a healthier complexion.
  7. Consider Non-Invasive Cosmetic Procedures- For those who have already experienced facial volume loss or sagging, non-invasive cosmetic treatments can help restore fullness and tighten the skin:
    • Dermal fillers can replace lost volume in areas like the cheeks, temples, and under the eyes.
    • Radiofrequency (RF) skin tightening treatments, such as Thermage, can stimulate collagen production and tighten loose skin.
    • Ultrasound therapies like Ultherapy use sound waves to lift and firm the skin without surgery. Always consult with a licensed professional before pursuing any cosmetic procedures.
  8. Protect Your Skin from UV Damage- Sun exposure can further degrade skin elasticity and accelerate the aging process. If you’re losing weight and want to prevent "Ozempic face," it’s crucial to wear sunscreen daily to protect your skin from UV damage, which can worsen sagging and wrinkles.
    • Use a broad-spectrum sunscreen with at least SPF 30. Reapply every two hours when outdoors.

The Bottom Line: Achieving Healthy Weight Loss While Maintaining Skin Health

"Ozempic face" may be a concern for those experiencing rapid weight loss, but it doesn’t have to be inevitable. By making conscious choices—focusing on gradual weight loss, eating a nutrient-rich diet, staying hydrated, and incorporating skin-boosting practices—you can avoid the more severe side effects of weight loss on your face. Additionally, treatments like fillers or skin-firming procedures are available if needed.

Maintaining overall wellness is about balance. As you pursue your weight loss goals, consider your skin’s health as part of your overall wellness strategy, ensuring you look and feel your best, both inside and out.